Complete Recovery of Central Pontine Myelinolysis by High Dose Pulse Therapy with Methylprednisolone

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Central pontine myelinolysis.

Central pontine myelinolysis (CPM), a neurologic disorder caused most frequently by rapid correction of hyponatremia, is characterized by demyelination that affects the central portion of the base of the pons. There are no inflammatory changes, and blood vessels are normal. Clinical features usually reflect damage to the descending motor tracts and include spastic tetraparesis, pseudobulbar par...

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Central pontine myelinolysis.

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Central pontine myelinolysis

Introduction Central pontine myelinolysis (CPM) in alcoholics and malnourished patients was first described by Adams, Victor and Mancall in 1959. This commonly fatal demyelinative process that involves the pons almost exclusively, is of unknown aetiology. In the majority of the published cases, CPM was associated with chronic alcoholism, malnutrition and electrolyte abnormalities, particularly ...

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Central pontine myelinolysis.

The case is described of a 46 year old female alcoholic, presenting with confusion, jaundice and reduced level of consciousness. The patient was hyponatraemic on admission and despite gradual correction of serum sodium the patient deteriorated neurologically. Magnetic Resonance Imaging scan of the brain revealed characteristic findings of Central Pontine Myelinolysis (CPM). We provide an overvi...

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ژورنال

عنوان ژورنال: Nihon Naika Gakkai Zasshi

سال: 2007

ISSN: 0021-5384,1883-2083

DOI: 10.2169/naika.96.2291